MERFISH analysis of the developing human neocortex

[ DOI: https://doi.org/10.35077/g.1156 ]

 

Dataset Citation:

Wang, Li. (2024). MERFISH analysis of the developing human neocortex. [ Collection / Dataset ]. Brain Image Library. https://doi.org/10.35077/g.1156

 

Abstract:

This dataset is a set of MERFISH experiments to identify the cell types and their locations in the developing human prefrontal and visual cortex. To generate a spatiotemporal atlas of individual cell types and major neuronal lineages in the developing human cerebral cortex, we performed spatial transcriptomic analysis using MERFISH in the prefrontal cortex. These data allow precise quantification of molecularly defined cell types as well as mapping their spatial distributions in a tissue context.

 

Methods:

https://vizgen.com/resources/user-guides/

 

Funding:

National Institutes of Health 5-U01-MH114825-05 A Cellular Resolution Census of the Developing Human Brain;
National Institutes of Health 5-R35-NS097305-07 Development and Expansion of the Human Cerebral Cortex

 

Contributors:

Wang, Li (Researcher) [ORCID: https://orcid.org/0000-0001-9510-6294 ] University of California, San Francisco
Kriegstein, Arnold (ProjectLeader) [ORCID: https://orcid.org/0000-0001-5742-2990 ] University of California, San Francisco

 

Related Identifiers:

IsCitedBy [ DOI : https://doi.org/10.1101/2024.01.16.575956 ];
Requires [ URL : https://download.brainimagelibrary.org/67/b0/67b0f446e818fc95/NIH-4365-BA10/ ];
Requires [ URL : https://download.brainimagelibrary.org/67/b0/67b0f446e818fc95/ARKFrozen-62-PFC/ ];
Requires [ URL : https://download.brainimagelibrary.org/f4/e6/f4e6e00f004c85ba/UCSF2018-003-MFG/ ];
Requires [ URL : https://download.brainimagelibrary.org/f4/e6/f4e6e00f004c85ba/ARKFrozen-65-V1/ ];
Requires [ URL : https://download.brainimagelibrary.org/f4/e6/f4e6e00f004c85ba/NIH-5900-BA17/ ];
Requires [ URL : https://download.brainimagelibrary.org/f4/e6/f4e6e00f004c85ba/NIH-4392-BA17/ ];