Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits
Dataset Citation:
Ting, Jonathan,
Tasic, Bosiljka,
Levi, Boaz,
Daigle, Tanya,
Bakken, Trygve.
(2024). Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits. [ Collection / Dataset ].
Brain Image Library.
https://doi.org/10.35077/g.1159
Abstract:
Cell type-specific regulatory elements were identified, enhancer-AAV viruses with fluorescent tags were generated and delivered into
the brains of wild-type or transgenic mice and characterized using the following methods: (1) Four or five sagittal sections
spanning different regions of interest (ROIs) from the virus-infected brains were imaged on a VERSA epifluorescence microscope to
characterize labeling patterns. (2) Serial coronal sections of virus-infected brains were imaged on a Tissuecyte 2P tomography
system to characterize labeling patterns brain-wide.
Funding:
National Institutes of Health 1-UF1-MH128339-01 Open-Access AAV Toolbox for Basal Ganglia Cell Types and Circuits;
National Institutes of Health 1-RF1-MH114126-01 Development of tools for cell-type specific labeling of human and mouse neocortical neurons ;
Allen Institute for Brain Sciences AIBS-internal Genetic Tools
Contributors:
Ting, Jonathan (ProjectLeader)
[ORCID:
https://orcid.org/0000-0001-8266-0392 ]
Allen Institute for Brain Science
Tasic, Bosiljka (ProjectLeader)
[ORCID:
https://orcid.org/0000-0002-6861-4506 ]
Allen Institute for Brain Science
Levi, Boaz (ProjectLeader)
[ORCID:
https://orcid.org/0000-0002-8346-872X ]
Allen Institute for Brain Science
Daigle, Tanya (ProjectLeader)
[ORCID:
https://orcid.org/0000-0001-9700-8452 ]
Allen Institute for Brain Science
Bakken, Trygve (ProjectLeader)
[ORCID:
https://orcid.org/0000-0003-3373-7386 ]
Allen Institute for Brain Science
Hunker, Avery (Researcher)
[ORCID:
https://orcid.org/0000-0003-0508-3637 ]
Allen Institute for Brain Science
Wirthlin, Morgan (Researcher)
[ORCID:
https://orcid.org/0000-0001-7967-7070 ]
Allen Institute for Brain Science
Johansen, Nelson (Researcher)
[ORCID:
https://orcid.org/0000-0002-4436-969X ]
Allen Institute for Brain Science
Ben-Simon, Yoav (Researcher)
[ORCID:
https://orcid.org/0000-0002-7075-097X ]
Allen Institute for Brain Science
Hooper, Marcus (Researcher)
[ORCID:
https://orcid.org/0000-0003-1228-5958 ]
Allen Institute for Brain Science
Way, Sharon (ProjectManager)
[ORCID:
https://orcid.org/0000-0002-9598-2240 ]
Allen Institute for Brain Science
Thyagarajan, Bargavi (ProjectManager)
[ORCID:
https://orcid.org/0000-0003-3871-6410 ]
Allen Institute for Brain Science
Opitz-Araya, Ximena (Researcher)
[ORCID:
https://orcid.org/0000-0003-4960-3622 ]
Allen Institute for Brain Science
Omstead, Victoria (Researcher)
[ORCID:
https://orcid.org/0000-0002-3796-970X ]
Allen Institute for Brain Science
Weed, Natalie (Researcher)
[ORCID:
https://orcid.org/0000-0003-0891-0327 ]
Allen Institute for Brain Science
Martinez, Refugio (Researcher)
[ORCID:
https://orcid.org/0009-0007-3737-3862 ]
Allen Institute for Brain Science
Groce, Erin (Researcher)
[ORCID:
https://orcid.org/0009-0008-6357-2774 ]
Allen Institute for Brain Science
Gore, Bryan (Researcher)
[ORCID:
https://orcid.org/0000-0003-1721-4235 ]
Allen Institute for Brain Science
Mich, John (Researcher)
[ORCID:
https://orcid.org/0000-0002-1626-1139 ]
Allen Institute for Brain Science
Roth, Jada (Researcher)
[ORCID:
https://orcid.org/0000-0001-7946-2176 ]
Allen Institute for Brain Science
Bishaw, Yeme (Researcher)
[ORCID:
https://orcid.org/0000-0002-8837-7827 ]
Allen Institute for Brain Science
Dwivedi, Deepanjali (Researcher)
[ORCID:
https://orcid.org/0000-0001-9992-9167 ]
Allen Institute for Brain Science
Yao, Shenqin (Researcher)
[ORCID:
https://orcid.org/0000-0003-2992-4752 ]
Allen Institute for Brain Science
Donadio, Nick (Researcher)
[ORCID:
https://orcid.org/0000-0002-6250-1148 ]
Allen Institute for Brain Science
Ronellenfitch, Kara (Researcher)
[ORCID:
https://orcid.org/0009-0007-6221-8485 ]
Allen Institute for Brain Science
Halterman, Carliana (Researcher)
[ORCID:
https://orcid.org/0009-0006-2297-2590 ]
Allen Institute for Brain Science
Desierto, Marie (Researcher)
[ORCID:
https://orcid.org/0009-0001-0092-7303 ]
Allen Institute for Brain Science
Waters, Jack (Researcher)
[ORCID:
https://orcid.org/0000-0002-2312-4183 ]
Allen Institute for Brain Science
Potekhina, Lydia (Researcher)
[ORCID:
https://orcid.org/0000-0001-8879-7920 ]
Allen Institute for Brain Science
Juneau, Zoe (Researcher)
[ORCID:
https://orcid.org/0000-0002-8860-5260 ]
Allen Institute for Brain Science
Reding, Melissa (Researcher)
[ORCID:
https://orcid.org/0000-0001-9845-1827 ]
Allen Institute for Brain Science
Liang, Elizabeth (Researcher)
[ORCID:
https://orcid.org/0009-0000-1781-6784 ]
Allen Institute for Brain Science
Departee, Max (Researcher)
[ORCID:
https://orcid.org/0009-0002-3723-6474 ]
Allen Institute for Brain Science
Sevigny, Joshua (Researcher)
[ORCID:
https://orcid.org/0000-0002-9297-4800 ]
Allen Institute for Brain Science
Bowlus, Jessica (Researcher)
[ORCID:
https://orcid.org/0009-0009-7335-3855 ]
Allen Institute for Brain Science
Rette, Dean (Researcher)
[ORCID:
https://orcid.org/0009-0002-5202-6627 ]
Allen Institute for Brain Science
Huang, Cindy (Researcher)
[ORCID:
https://orcid.org/0009-0002-5386-6345 ]
Allen Institute for Brain Science
Shulga, Lyudmila (Researcher)
[ORCID:
https://orcid.org/0009-0002-9785-328X ]
Allen Institute for Brain Science
Smith, Kimberly (Researcher)
[ORCID:
https://orcid.org/0000-0002-3142-1970 ]
Allen Institute for Brain Science
Gary, Amanda (Researcher)
[ORCID:
https://orcid.org/0000-0002-6397-1520 ]
Allen Institute for Brain Science
McGraw, Medea (Researcher)
[ORCID:
https://orcid.org/0000-0001-5267-489X ]
Allen Institute for Brain Science
Bomben, Jasmine (Researcher)
[ORCID:
https://orcid.org/0000-0003-3965-5373 ]
Allen Institute for Brain Science
Maxwell, Michelle (Researcher)
[ORCID:
https://orcid.org/0000-0001-7434-5667 ]
Allen Institute for Brain Science
Ruiz, Augustin (Researcher)
[ORCID:
https://orcid.org/0000-0002-8361-5152 ]
Allen Institute for Brain Science
Pom, Christina (Researcher)
[ORCID:
https://orcid.org/0000-0001-9057-040X ]
Allen Institute for Brain Science
Malone, Jocelin (Researcher)
[ORCID:
https://orcid.org/0000-0003-0794-4250 ]
Allen Institute for Brain Science
Brouner, Krissy (Researcher)
[ORCID:
https://orcid.org/0000-0001-5790-7154 ]
Allen Institute for Brain Science
Egdorf, Tom (Researcher)
[ORCID:
https://orcid.org/0000-0001-9059-8904 ]
Allen Institute for Brain Science
Barta, Stuard (Researcher)
[ORCID:
https://orcid.org/0000-0001-7180-3466 ]
Allen Institute for Brain Science
Oyama, Alana (Researcher)
[ORCID:
https://orcid.org/0000-0002-4492-0533 ]
Allen Institute for Brain Science
Ariza, Jeanelle (Researcher)
[ORCID:
https://orcid.org/0000-0002-0829-7887 ]
Allen Institute for Brain Science
Alaya, Angela (Researcher)
[ORCID:
https://orcid.org/0009-0002-8512-6851 ]
Allen Institute for Brain Science
Sigler, Ana (Researcher)
[ORCID:
https://orcid.org/0000-0002-5094-8073 ]
Allen Institute for Brain Science
Morin, Elyse (Researcher)
[ORCID:
https://orcid.org/0000-0002-7310-1561 ]
Allen Institute for Brain Science
Lusk, Nicholas (Researcher)
[ORCID:
https://orcid.org/0000-0001-6346-2083 ]
Allen Institute for Brain Science
Taormina, Mike (Researcher)
[ORCID:
https://orcid.org/0000-0003-4634-4039 ]
Allen Institute for Brain Science
Related Identifiers:
Requires
[ URL :
https://download.brainimagelibrary.org/77/43/774317f96671fbd7/ ];
Requires
[ URL :
https://download.brainimagelibrary.org/07/7d/077dbfded4d55b5e/ ];