Confocal imaging of transcriptional crosstalk between AAV genomes carrying different enhancers in the mouse brain

[ DOI: https://doi.org/10.35077/g.1163 ]

 

Dataset Citation:

Gradinaru, Viviana, Gradinaru Lab. (2024). Confocal imaging of transcriptional crosstalk between AAV genomes carrying different enhancers in the mouse brain. [ Collection / Dataset ]. Brain Image Library. https://doi.org/10.35077/g.1163

 

Abstract:

This data collection contains images of brains of mice transduced with viral vectors carrying different regulatory elements and reporters to study transcriptional crosstalk between AAV genomes. The data is described in the publication "Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo."

 

Funding:

National Institutes of Health 1-UF1-MH128336-01   Engineered AAV Identification, Validation, and Dissemination Pipeline for Brain Cell Type-Specific Manipulation Across Species;
Chan Zuckerberg Initiative https://doi.org/10.37921/447155kijhgw Non-Canonical Pathways Towards Rescue from Neurodegenerative States;
Natural Sciences and Engineering Research Council of Canada NA Postgraduate Scholarship – Doctoral

 

Contributors:

Gradinaru, Viviana (ProjectLeader) [ORCID: https://orcid.org/0000-0001-5868-348X ] California Institute of Technology
Gradinaru Lab (ResearchGroup) California Institute of Technology

 

Related Identifiers:

IsCitedBy [ DOI : https://doi.org/10.1101/2023.12.23.573214 ];
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Requires [ URL : https://download.brainimagelibrary.org/90/44/90440f3036b24e45/ ];
Requires [ URL : https://download.brainimagelibrary.org/77/19/771981d5daf3ce0b/ ];