The synaptic basis of activity-dependent eye-specific competition

[ DOI: https://doi.org/10.35077/g.1164 ]

 

Dataset Citation:

Speer, Colenso, Zhang, Chenghang. (2024). The synaptic basis of activity-dependent eye-specific competition. [ Collection / Dataset ]. Brain Image Library. https://doi.org/10.35077/g.1164

 

Abstract:

This data set is a series of four-color volumetric super-resolution microscopy reconstructions of retinogeniculate synapses in the developing mouse dorsal lateral geniculate nucleus. The imaging technique was single-molecule localization using Stochastic Optical Reconstruction Microscopy (STORM). The data set includes volumetric .tiff image stacks from wild-type mice and a genetic mutant mouse line with abnormal retinal wave activity during postnatal development (B2KO mouse). Three separate postnatal time points were imaged during the first week of development (P2/P4/P8). The data set includes images from biological triplicate samples at each time point and genotype. Images were taken in the future contralateral region of the dLGN.

 

Funding:

National Institutes of Health 1-DP2-MH125812-01 A molecular connectomics platform for multi-scale analysis of activity-dependent synapse development and plasticity

 

Contributors:

Speer, Colenso (ProjectLeader) [ORCID: https://orcid.org/0000-0002-3076-7072 ] University of Maryland, College Park
Zhang, Chenghang (DataCollector) [ORCID: https://orcid.org/0000-0003-1346-2186 ] University of Maryland, College Park

 

Related Identifiers:

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IsCitedBy [ DOI : https://doi.org/10.1016/j.celrep.2023.112085 ];
IsCitedBy [ DOI : https://doi.org/10.1101/2023.09.28.560055 ];